Mechano-metabolic regulation of ion channel function in engineered heart muscle

We are excited to start an NSF funded CAREER award that will allow us to study how mechanical forces integrate with metabolic signaling to regulate channel function in stem cell derived heart tissue. This award will also support outreach with local K-12 institutions through Washington University’s Institute for School Partnership.

Congratulations to Daniel Simmons

Congratulations to Daniel Simmons
Congratulations to Daniel Simmons for the publication of his paper, Hydrogel-Assisted Double Molding Enables Rapid Replication of Stereolithographic 3D Prints for Engineered Tissue Design in ACS Applied Material Interfaces! https://doi.org/10.1089/ten.tec.2022.0053

Congratulations to Soore Oguntuyo and David Schuftan

Congratulations to Soore Oguntuyo and David Schuftan
Congratulations to Soore Oguntuyo and David Schuftan for the publication of their paper, IRobust, Automated Analysis of Action Potential and Calcium Transient Morphology in iPSC-Derived Micro-Heart Muscle for In Vitro Assessment of Drug-Induced Toxicity in Tissue Engineering Part C Methods! https://doi.org/10.1089/ten.tec.2022.0053

Harper Jiang Passes PhD Qualifying Exam

Harper Jiang Passes PhD Qualifying Exam
Congratulations to Harper Jiang for passing her qualifying exam and officially becoming a PhD candidate in the Department of Biomedical Engineering!

Congratulations to Xiaohong Tan

Congratulations to Xiaohong Tan
Congratulations to Xiaohong Tan for the publication of her paper, Integrin and syndecan binding peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype in Biomaterials! https://doi.org/10.1016/j.biomaterials.2021.121113

Huebsch Lab Receives Nearly $2 Million Grant from the NIH to Study Potential Mechanical Triggers Behind Inherited Heart Disease (Links to an external site)

Huebsch Lab Receives Nearly $2 Million Grant from the NIH to Study Potential Mechanical Triggers Behind Inherited Heart Disease
Nathaniel Huebsch, assistant professor of biomedical engineering in the McKelvey School of Engineering at Washington University in St. Louis, will research the role that blood pressure plays in triggering symptoms in patients with hypertrophic cardiomyopathy with a five-year, nearly $2 million grant from the National Institutes of Health. He and his team will use a heart tissue model engineered from human induced pluripotent stem cells (iPSCs) to identify molecular mechanisms that cause that sensitize heart muscle to the mechanical load imparted by hypertension. […]

Ghiska Ramahdita Wins Audience Choice Award at Reach Out SciComm Slam Final

Ghiska Ramahdita Wins Audience Choice Award at Reach Out SciComm Slam Final
Ghiska Ramahdita, a doctoral student in The Center for Engineering MechanoBiology (CEMB) in the McKelvey School of Engineering, was voted the Audience Choice Award winner of the National Science Foundation’s Science and Technology Centers Reach Out Challenge semifinal round, hosted by the Museum of Science in Boston. Ramahdita is a second-year doctoral student in mechanical engineering […]

Mimi Guo receives American Heart Association Fellowship

Mimi Guo receives American Heart Association Fellowship
Jingxuan (Mimi) Guo, a doctoral student in mechanical engineering & materials science in the McKelvey School of Engineering, has received a two-year, $63,040 predoctoral fellowship from the American Heart Association to investigate how mechanical factors influence the development of hypertrophic cardiomyopathy (HCM), the most frequent cause of sudden death in young patients and the most […]

Ghiska Ramahdita named finalist in Reach Out SciComm Slam

Ghiska Ramahdita named finalist in Reach Out SciComm Slam
Ghiska Ramahdita, a doctoral student in The Center for Engineering MechanoBiology (CEMB) in the McKelvey School of Engineering, was named the judges’ choice winner of the National Science Foundation’s Science and Technology Centers Reach Out Challenge semifinal round, hosted by the Museum of Science in Boston.  Using captivating imagery, videos and props, Ramahdita succinctly described her […]

Ghiska Ramahdita named a semifinalist in the 2021 Reach Out Science Slam Communication Challenge jointly sponsored by the National Science Foundation and the Museum of Science, Boston

Ghiska Ramahdita named a semifinalist in the 2021 Reach Out Science Slam Communication Challenge jointly sponsored by the National Science Foundation and the Museum of Science, Boston
Congratulations to Ghiska Ramahdita on being named a semifinalist in the 2021 Reach Out Science Slam Communication Challenge jointly sponsored by the National Science Foundation and the Museum of Science, Boston. The Reach Out Science Slam is a nationwide effort to boost the communication skills of students and early-career researchers affiliated with the National Science […]

Congratulations to Era Jain and Sydney Neal

Congratulations to Era Jain and Sydney Neal
Congratulations to Era Jain and Sydney Neal for publication of their paper, Copper-Free Azide–Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels in ACS Applied Biomaterials! https://doi.org/10.1021/acsabm.0c00976

Congratulations to Mimi Guo!

Congratulations to Mimi Guo!
Congratulations to Jingxuan (Mimi) Guo for publication of her paper, Elastomer-Grafted iPSC-Derived Micro Heart Muscles to Investigate Effects of Mechanical Loading on Physiology in ACS Biomaterials Science & Engineering! https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c00318

Ghiska Ramahdita Passes PhD Qualifying Exam

Ghiska Ramahdita Passes PhD Qualifying Exam
Congratulations to Ghiska Ramahdita for passing her qualifying exam and officially becoming a PhD student in the Department of Mechanical Engineering and Materials Sciences!

Mimi Guo Passes PhD Qualifying Exam

Mimi Guo Passes PhD Qualifying Exam
Congratulations to Jingxuan (Mimi) Guo for passing her qualifying exam and officially becoming a PhD student in the Department of Mechanical Engineering and Materials Sciences!

Awarded Career Development Grant

Awarded Career Development Grant
We are grateful to receive support from the American Heart Association to investigate mechanisms of preload-induced pathology in genetically inherited Arrhythmogenic Cardiomyopathy, a leading cause of sudden cardiac death in young athletes. Read more here.

Daniel Simmons Passes PhD Qualifying Exam

Daniel Simmons Passes PhD Qualifying Exam
Congratulations to Daniel Simmons for passing his qualifying exam and officially becoming a PhD student in the Department of Biomedical Engineering!