Congrats Dr. Neal
Congratulations to Dr. Sydney Neal for her successful oral defense yesterday on her work developing ways to enhance the potency of growth factor mimicking peptides.
Studying the impact of anti-inflammatory peptides on stem cell therapies in the disc
We are excited to begin studies, with support from a 2-year R21 grant from NIH-NIAMS, to identify how IGF-1 mimetic peptides can support the ability of Mesenchymal Stromal Cells to augment repair and dampen inflammation in the intervertebral disc. These studies will leverage our long-standing collaboration with Drs. Lori Setton (WashU BME) and Munish Gupta […]
Welcome Dr. Hashemi!
We welcome Dr. Mohammad Hashemi, who joins our team from the Lipke Lab at Auburn University, where he developed new ways to use biomaterials for scalable cardiomyocyte production from iPSC. Mohammad will lead efforts to control Mesenchymal Stromal Cell immunomodulation with hydrogel materials in the lab.
New review published
Congrats to Yasaman on her review describing the combination of high resolution microscopy with engineered heart tissue technology in Frontiers in Mechanical Engineering!
Congratulations Dr. Tan!
Congratulations to our newest PhD graduate, Dr. Xiaohong Tan! Xiao successfully defended her PhD thesis on work showing how integrin binding peptides can combine with both adhesive and growth factor mimicking peptides to drive cell fate decisions.
Developing high-throughput vessel-on-a-chip technology to study hypoxia-induced hypertension
We are excited to start an American Heart Association funded Collaborative Sciences project led by Kel Vin Woo of WashU Pediatrics and David Ornitz of Developmental Biology, that will allow us to expand our rapid, 3D-printing based prototyping technologies to create blood-vessel on a chip platforms.
Mechano-metabolic regulation of ion channel function in engineered heart muscle
We are excited to start an NSF funded CAREER award that will allow us to study how mechanical forces integrate with metabolic signaling to regulate channel function in stem cell derived heart tissue. This award will also support outreach with local K-12 institutions through Washington University’s Institute for School Partnership.
Leveraging engineered heart tissues to study non-characterized genetic variants (Links to an external site)
We are excited to start an NIH-funded project to use our iPSC engineered heart muscles to study how uncharacterized “variants of unknown significance” lead to hypertrophic cardiomyopathy phenotypes, with lead-PI Sharon Cresci, MD. This work will leverage our micro-heart muscle array technology to study how both genetic variants and non-genetic forms of stress can affect […]
Motion Correction with Virtual Blebbistatin Software (Links to an external site)
Congrats to alumnus Mimi Guo and collaborators on their PNAS paper!
Yasaman Kargar Gaz Kooh Passes PhD Qualifying Exam
Congratulations to Yasaman Kargar Gaz Kooh for passing her qualifying exam and officially becoming a PhD candidate in the Institute of Materials Science and Engineering!
Congratulations to Daniel Simmons
Congratulations to Daniel Simmons for the publication of his paper, Hydrogel-Assisted Double Molding Enables Rapid Replication of Stereolithographic 3D Prints for Engineered Tissue Design in ACS Applied Material Interfaces! https://doi.org/10.1089/ten.tec.2022.0053
Congratulations to Dr. Daniel Wade Simmons on Successfully Defending His PhD Dissertation
Congratulations to Dr. Daniel Wade Simmons on successfully defending his doctoral dissertation: “Chronic Prestress Regulation of Cardiomyocyte Electrophysiology”
Congratulations to David Schuftan on Successfully Defending His Masters Thesis
Congratulations to David Schuftan on successfully defending his masters thesis: “A Magneto-Rheological Platform to Dynamically Control Afterload in Engineered Micro Heart Muscles”
Congratulations to Dr. Mimi Guo for Successfully Defending Her PhD Dissertation
Congratulations to Dr. Mimi Guo on successfully defending her doctoral dissertation: “Modeling the Effects of Mechanical Loading On Heart Disease Pathogenesis Using Human Induced Pluripotent Stem Cell”
Congratulations to Soore Oguntuyo and David Schuftan
Congratulations to Soore Oguntuyo and David Schuftan for the publication of their paper, IRobust, Automated Analysis of Action Potential and Calcium Transient Morphology in iPSC-Derived Micro-Heart Muscle for In Vitro Assessment of Drug-Induced Toxicity in Tissue Engineering Part C Methods! https://doi.org/10.1089/ten.tec.2022.0053
Huebsch Lab, in collaboration with Greenberg and Lavine Labs, awarded $300,000 grant from the AHA
We are excited to announce new support from the American Heart Association to support our collaborative work with Drs. Michael Greenberg (Department of Biochemistry and Molecular Biophysics) and Kory Lavine (Department of Cardiology) at the Washington University School of Medicine. This grant will allow us to combine our expertise to study how the immune system […]
Harper Jiang Passes PhD Qualifying Exam
Congratulations to Harper Jiang for passing her qualifying exam and officially becoming a PhD candidate in the Department of Biomedical Engineering!
Sydney Neal awarded three year F31 Fellowship
Congratulations to receiving a three year F31 fellowship from NIH-NIAMS!
Congratulations to Xiaohong Tan
Congratulations to Xiaohong Tan for the publication of her paper, Integrin and syndecan binding peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype in Biomaterials! https://doi.org/10.1016/j.biomaterials.2021.121113
Huebsch Lab Receives Nearly $2 Million Grant from the NIH to Study Potential Mechanical Triggers Behind Inherited Heart Disease (Links to an external site)
Nathaniel Huebsch, assistant professor of biomedical engineering in the McKelvey School of Engineering at Washington University in St. Louis, will research the role that blood pressure plays in triggering symptoms in patients with hypertrophic cardiomyopathy with a five-year, nearly $2 million grant from the National Institutes of Health. He and his team will use a heart tissue model engineered from human induced pluripotent stem cells (iPSCs) to identify molecular mechanisms that cause that sensitize heart muscle to the mechanical load imparted by hypertension. […]
Ghiska Ramahdita Wins Audience Choice Award at Reach Out SciComm Slam Final
Ghiska Ramahdita, a doctoral student in The Center for Engineering MechanoBiology (CEMB) in the McKelvey School of Engineering, was voted the Audience Choice Award winner of the National Science Foundation’s Science and Technology Centers Reach Out Challenge semifinal round, hosted by the Museum of Science in Boston. Ramahdita is a second-year doctoral student in mechanical engineering […]
Mimi Guo receives American Heart Association Fellowship
Jingxuan (Mimi) Guo, a doctoral student in mechanical engineering & materials science in the McKelvey School of Engineering, has received a two-year, $63,040 predoctoral fellowship from the American Heart Association to investigate how mechanical factors influence the development of hypertrophic cardiomyopathy (HCM), the most frequent cause of sudden death in young patients and the most […]
Ghiska Ramahdita named finalist in Reach Out SciComm Slam
Ghiska Ramahdita, a doctoral student in The Center for Engineering MechanoBiology (CEMB) in the McKelvey School of Engineering, was named the judges’ choice winner of the National Science Foundation’s Science and Technology Centers Reach Out Challenge semifinal round, hosted by the Museum of Science in Boston. Using captivating imagery, videos and props, Ramahdita succinctly described her […]
Ghiska Ramahdita named a semifinalist in the 2021 Reach Out Science Slam Communication Challenge jointly sponsored by the National Science Foundation and the Museum of Science, Boston
Congratulations to Ghiska Ramahdita on being named a semifinalist in the 2021 Reach Out Science Slam Communication Challenge jointly sponsored by the National Science Foundation and the Museum of Science, Boston. The Reach Out Science Slam is a nationwide effort to boost the communication skills of students and early-career researchers affiliated with the National Science […]
Congratulations to Era Jain and Sydney Neal
Congratulations to Era Jain and Sydney Neal for publication of their paper, Copper-Free Azide–Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels in ACS Applied Biomaterials! https://doi.org/10.1021/acsabm.0c00976
Congratulations to Mimi Guo!
Congratulations to Jingxuan (Mimi) Guo for publication of her paper, Elastomer-Grafted iPSC-Derived Micro Heart Muscles to Investigate Effects of Mechanical Loading on Physiology in ACS Biomaterials Science & Engineering! https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c00318
Ghiska Ramahdita Passes PhD Qualifying Exam
Congratulations to Ghiska Ramahdita for passing her qualifying exam and officially becoming a PhD student in the Department of Mechanical Engineering and Materials Sciences!
Xiaohong Tan and Sydney Neal Pass PhD Qualifying Exam
Congratulations to Xiaohong Tan and Sydney Neal for passing their qualifying exams and officially becoming PhD students in the Department of Biomedical Engineering
Xiaohong Tan Awarded NSF Graduate Research Fellowship
Congratulations to Xiaohong Tan for being awarded the National Science Foundation Graduate Research Fellowship!
Mimi Guo Passes PhD Qualifying Exam
Congratulations to Jingxuan (Mimi) Guo for passing her qualifying exam and officially becoming a PhD student in the Department of Mechanical Engineering and Materials Sciences!
Awarded Career Development Grant
We are grateful to receive support from the American Heart Association to investigate mechanisms of preload-induced pathology in genetically inherited Arrhythmogenic Cardiomyopathy, a leading cause of sudden cardiac death in young athletes. Read more here.
Daniel Simmons Passes PhD Qualifying Exam
Congratulations to Daniel Simmons for passing his qualifying exam and officially becoming a PhD student in the Department of Biomedical Engineering!